Ischemia-Reperfusion Changes in Rat Skeletal Muscle Morphology
نویسندگان
چکیده
منابع مشابه
Colchicine protects rat skeletal muscle from ischemia/reperfusion injury by suppressing oxidative stress and inflammation
Objective(s): Neutrophils play an important role in ischemia/reperfusion (IR) induced skeletal muscle injury. Microtubules are required for neutrophil activation in response to various stimuli. This study aimed to investigate the effects of colchicine, a microtubule-disrupting agent, on skeletal muscle IR injury in a rat hindlimb ischemia model. Materials and Methods: Twenty-one Sprague-Dawley ...
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Leukocytes have been shown to contribute to ischemia-reperfusion injury in skeletal muscle. Pentoxifylline (PTXF), a xanthine-derived phosphodiesterase inhibitor, has received recent attention because of its action on leukocytes. To clarify the effects of PTXF in reperfusion injury, we measured the resting transmembrane potential difference ( E m) and evaluated postcapillary venule microcircula...
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BACKGROUND Resveratrol, a polyphenol found in grape and red wine, was previously shown to have free radical scavenging and antioxidant properties in various tissues. In this study, the effects of resveratrol were investigated in muscle tissue concerning the ischemia reperfusion (I/R) injury of rat hindlimb. METHODS Arterial circulation of right hindlimbs of 24 Sprague-Dawley rats was ceased b...
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B. M. Damon, J. L. Hornberger, J. A. Kent-Braun Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States, Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, Exercise Science, University of Massachusetts, Amherst, MA, United States Introduction Transient MRI signal intensity (SI) increases can be observed after brief isometric contr...
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ژورنال
عنوان ژورنال: Rigakuryoho Kagaku
سال: 2012
ISSN: 1341-1667,2434-2807
DOI: 10.1589/rika.27.91